Minimally invasive evacuation of spontaneous intracerebral hemorrhage using sonothrombolysis
نویسندگان
چکیده
منابع مشابه
Minimally invasive evacuation of spontaneous intracerebral hemorrhage using sonothrombolysis.
OBJECT Catheter-based evacuation is a novel surgical approach for the treatment of brain hemorrhage. The object of this study was to evaluate the safety and efficacy of ultrasound in combination with recombinant tissue plasminogen activator (rt-PA) delivered through a microcatheter directly into spontaneous intraventricular (IVH) or intracerebral (ICH) hemorrhage in humans. METHODS Thirty-thr...
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With new therapies and interventions in the ischemic stroke realm leading to improved outcomes, attention is turning to treatment of hemorrhagic stroke therapies that strive to improve both morbidity and mortality. The thought that “time is brain” likely also applies to damage to neural structures neighboring hemorrhagic clots and efforts to create a method for hemorrhagic clot evacuation while...
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Spontaneous intracerebral hemorrhage is a common subtype of stroke with high incidence rates and mortality worldwide of which over two thirds of deaths are in developing countries, where are >100 000 deaths and approximately 300 000 disabilities annually in China. Supratentorial spontaneous intracerebral hemorrhage (SICH), which accounts for 78% to 88% of intracerebral hemorrhages, is primarily...
متن کاملSpontaneous Intracerebral and Intraventricular Hemorrhage: Advances in Minimally Invasive Surgery and Thrombolytic Evacuation, and Lessons Learned in Recent Trials.
Optimal management of spontaneous intracerebral hemorrhage (ICH) remains one of the highly debated areas in the field of neurosurgery. Earlier studies comparing open surgical intervention with best medical management failed to show a clear benefit. More recent experience with minimally invasive techniques has shown greater promise. Well-designed phase II trials have confirmed the safety and pre...
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Background. Spontaneous intracerebral hemorrhage (ICH) is common and causes significant mortality and morbidity. To date, optimal medical and surgical intervention remains uncertain. A lack of definitive benefit for operative management may be attributable to adverse surgical effect, collateral tissue injury. This is particularly relevant for ICH in dominant, eloquent cortex. Minimally invasive...
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ژورنال
عنوان ژورنال: Journal of Neurosurgery
سال: 2011
ISSN: 0022-3085,1933-0693
DOI: 10.3171/2011.5.jns10505